Rotational Dynamics of Phospholamban Determined by Multifrequency Electron Paramagnetic Resonance
نویسندگان
چکیده
منابع مشابه
Rotational dynamics of phospholamban determined by multifrequency electron paramagnetic resonance.
We have used multifrequency electron paramagnetic resonance to define the multistate structural dynamics of an integral membrane protein, phospholamban (PLB), in a lipid bilayer. PLB is a key regulator of cardiac calcium transport, and its function requires transitions between distinct states of intramolecular dynamics. Monomeric PLB was synthesized with the TOAC spin label at positions 11 (in ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2007
ISSN: 0006-3495
DOI: 10.1529/biophysj.107.108910